Archive
HIV – immunity and vaccine development
HIV infection induces both humoral and cytotoxic immune response. HIV is extremely efficient in evading host immune response due to virus adaptability. An immune response early in the course of…
Read more ›Influence of hysteroscopic resection of septate uterus on reproductive prognosis and pregnancy
Septate uterus is one of the cogenital abnormalities that causes the most problems. It is frequently the cause of spontaneous abortion, preterm labour, malpresentation or intrauterine growth retardation. Recently, hysteroscopic…
Read more ›Incidence of activated protein C resistance among patients with deep vein thrombosis
A group of 100 consecutive patients treated for deep vein thrombosis in the Trnovo Hospital of Internal Medicine from January 1992 to December 1994, was studied for the presence of…
Read more ›Surgical treatment of Achilles tendon rupture
Currently, open surgical repair and percutaneous operation are the two most commonly used operative techniques for the repair of ruptured Achilles tendon. Open surgery is being increasingly replaced by the…
Read more ›Childhood Nephrotic Syndrome – Case Report
Nephrotic syndrome is among the most common kidney diseases in children and it occurs as a result of damage to the glomerular filtration barrier. It is characterized by edema, nephrotic…
Read more ›Subcutaneous Emphysema of the Neck and Pneumomediastinum Following Isolated Facial Trauma
Traumatic pneumomediastinum is usually caused by severe thoracic injury, resulting in blunt or penetrating neck, chest or abdominal trauma. Subcutaneous emphysema of the neck and pneumomediastinum following facial trauma in…
Read more ›Autophagy and its Role in Health and in Sickness
Autophagy is a catabolic process of the degradation of cellular components by lysosomal enzymes. It is essential for cellular homeostasis by maintaining the balance between the synthesis, degradation and turnover…
Read more ›Molecular Mechanisms of Metastasis
The spread of metastases from a primary site through blood or the lymphatic system, which results in the establishment of secondary tumors in distant locations, is the main cause of…
Read more ›Tight Junction Barriers in Our Body
Tight junctions comprise a crucial part of epithelial barriers by forming a molecular pore like structure that encircles the apex of individual cells. They control the passage of small molecules…
Read more ›A Symphony of Maladies – Occupational Diseases in Musicians
Almost half of the musicians are confronted with playing-related health problems. The characteristics of an individual performer and the type of musical instrument played determine the musician's health problems. These…
Read more ›Bioterrorism
Bioterrorism is an attack on the health of the general population through an artificially induced epidemic of bacterial infectious diseases such as anthrax, plague, cholera, tularemia, brucellosis or botulism, and…
Read more ›Cytopathologic Diagnosis of Bladder Cancer in Urine and Bladder Washings
The cytopathologic examination of urine and bladder washings is a simple method for the detection of primary bladder cancer in symptomatic patients or in patients with hematuria. This method is…
Read more ›Biologic Drugs in Asthma Treatment
Development of the new antiasthmatic drugs is directed above all in the synthesis of theinhibitors of the proinflammatory cytokines and IgE antibodies. Several biologic drugs are tested for this purpose;…
Read more ›The Effect of Tactile Stimulation on Physiological Parameters, Behavioural Response and Phase Adjustment of Rest-activity Rhythms in Newborn Infants
BACKGROUND. Infant tactile stimulation reduces distress behaviours, improves pulmonary function, weight gain per day, bone mineralization, developmentally appropriate functioning, enhances sleep organization and early attachment between infant and parents. We…
Read more ›Medical History and Examination of Adult Patients with Infectious Disease
Infectious diseases are becoming more complicated to diagnose and treat. History plays a critical role in narrowing the differential diagnosis and deciding on the most appropriate diagnostic tests. Symptoms often…
Read more ›Differential Diagnosis in a Patient with Bilateral Pulmonary Infiltrates, Hypoxemia and Hemoptysis
Eighteen years old male with bilateral pulmonary infiltrates, hypoxia and hemoptysis was diagnosed with Goodpasture syndrome. We present a retrospective analysis of the clinical decision making that lead to the…
Read more ›Adolescent Coping with Chronic Disease
Adolescence is a developmental stage in which a person is learning to master cognitive, emotional, social and moral maturity. Adolescents growing up with chronic renal disease enter this stage later…
Read more ›Agents of Endemic Mycoses
The most important agents of endemic mycoses that can cause disease in healthy hosts are Histoplasma capsulatum, Blastomyces dermatitidis, Paracoccidioides brasiliensis and Coccidioides immitis. They occupy specific ecologic and geographic…
Read more ›Treatment Modalities in Endometriosis
Endometriosis is an estrogen dependent disease that affects 5-10% of women of reproductive age. The disease occurs most commonly on the uterosacral ligaments, in the pouch of Douglas, on the…
Read more ›Near-Death Experiences
Near-death experiences are experiences of deep feelings of out-of-body experiences and of entering other dimensions outside the usual borders of time and space. They mostly occur when a person is…
Read more ›Beneficial Effects of Red Wine in Preventing the Development of Atherosclerosis
Numerous preclinical and clinical studies have shown a correlation between the consumption of moderate amounts of red wine and a reduced risk of cardiovascular complications associated with atherosclerosis. Both polyphenolic…
Read more ›Cardiogenic Shock
Cardiogenic shock is a state of tissue hypoperfusion that involves signs of progressive tissue injury due to failing heart function. Cardiogenic shock can develop as a consequence of myocardial disease/injury,…
Read more ›Clinical, Immunological and Genetic Characteristics of Patients with Autoimmune Lymphoproliferative Syndrome in Slovenia
BACKGROUND. Autoimmune lymphoproliferative syndrome (ALPS) is a primary immunodeficiency disorder characterized by immune dysregulation. ALPS is defined as chronic, nonmalignant lymphoproliferation in patients with double-negative T cell (DNT) expansion over…
Read more ›Erythrocyte shape and deformability due to variations in external factors
Changes in erythrocyte shape are necessary in the circulation of blood, therefore deformability is one of the basic properties of erythrocytes. A research project was conducted in order to determine…
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